2021 Model Year

Mercedes-Benz E-Class

NHTSA Complaints & Reliability Data

Compare
Complaints
18
Recalls
0
Crashes
0
Severe
1

Recent Complaints

Latest owner reports

Power Train
Apr 2026

With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of...

Engine
Dec 2025

Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the ve...

Power Train
Oct 2025

The Mercedes E350, with 22,000 miles suffered a catastrophic transmission failure while driving on the highway. I managed to exit the highway but the...

Engine
Jul 2025

My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as...

ELECTRICAL SYSTEM,BACK OVER PREVENTION
Mar 2025

1) Rear view camera sometimes working, some times not working. (Message reads “system inoperative “ 2) Forward view camera also affected. 3) displ...

ELECTRICAL SYSTEM,ENGINE,FUEL/PROPULSION SYSTEM
Sep 2024

The engine is misfiring and not powering correctly during driving. Car is failing to take off and today almost caused an accident due to the car would...

ELECTRICAL SYSTEM,ENGINE Fire
Jul 2024

FIRE FIRE FIRE Information light came on just saying 12 Volt Battery. I sat in the car letting it idle for about 3 minutes. It began to smoke and th...

BACK OVER PREVENTION
May 2024

I was parking and the 360 view sensor did not come up. When I tried to back out and move forward again, I realized the back up camera would not come o...

Brakes
Mar 2024

The contact owns a 2021 Mercedes-Benz E350. The contact stated that while parking the vehicle the emergency brake independently seized. The contact...

Fuel System
Jan 2024

The contact owns a 2021 Mercedes-Benz E350. The contact stated while driving at approximately 60 MPH, the check engine warning light illuminated, and...

VS

Vehicle Safety Research Team

Automotive Data Analysts

Independent researchers analyzing NHTSA data to help consumers make informed vehicle decisions.

Data updated: March 5, 2026

Summary

The 2021 Mercedes-Benz E-Class has 18 complaints and 0 recalls on record. The most commonly reported issue is Engine.

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